Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 9/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343945 | 0.87 | PTPN5 (0.46) | PTPN5GGPS1PTPN1FDPS | |
| SCHEMBL1354398 | 0.75 | MEN1 (0.42) | PTPN5ACP3GGPS1 | |
| SCHEMBL8992169 | 0.75 | PTPN5 (0.40) | PTPN5ACP3GGPS1PTPN1 | |
| SCHEMBL9344792 | 0.74 | GRIN2D (0.46) | PTPN5GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9445936 | 0.74 | PGK1 (0.45) | PTPN5ACP3GGPS1PTPN1FDPS | |
| SCHEMBL9445920 | 0.73 | PTPN1 (0.39) | PTPN1FDPS | |
| SCHEMBL5859053 | 0.72 | PTPN5 (0.46) | PTPN5GGPS1PTPN1 | |
| SCHEMBL23908217 | 0.70 | PGK1 (0.43) | PTPN5PTPN1FDPS | |
| SCHEMBL1338013 | 0.67 | PGK1 (0.44) | PTPN5ACP3GGPS1 | |
| SCHEMBL7870277 | 0.66 | PGK1 (0.44) | PTPN5PTPN1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321016-A | Epliepsy, central nervous system disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5162311-A | Treating epilepsy, psychiatric disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1992-11-10 | — | — | US | disclosed |