Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 4/20 | 0.45 |
| ▸ | PGK2 | P07205 | 4/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 7/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390400 | 0.85 | PGK1 (0.52) | PGK1PGK2ACP3PTPN5PTPN1 | |
| SCHEMBL9445969 | 0.82 | TAAR1 (0.51) | PGK1PGK2ACP3 | |
| SCHEMBL1362338 | 0.81 | MEN1 (0.41) | PGK1PGK2PTPN5PTPN1CYP1A2 | |
| SCHEMBL9445996 | 0.81 | PGK1 (0.42) | PGK1PGK2ACP3PTPN5PTPN1 | |
| SCHEMBL9445920 | 0.80 | PTPN1 (0.39) | PGK1PGK2PTPN1FDPS | |
| SCHEMBL9343945 | 0.79 | PTPN5 (0.46) | PGK1PGK2PTPN5PTPN1GGPS1 | |
| SCHEMBL2031911 | 0.78 | TSHR (0.43) | PGK1PGK2PTPN5PTPN1FDPS | |
| SCHEMBL1338013 | 0.78 | PGK1 (0.44) | PGK1PGK2ACP3PTPN5GGPS1 | |
| SCHEMBL29024551 | 0.78 | PGK1 (0.53) | PGK1PGK2ACP3PTPN5PTPN1 | |
| SCHEMBL27887459 | 0.78 | PGK1 (0.41) | PGK1PGK2ACP3PTPN5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |