Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 6/20 | 0.52 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846854 | 0.92 | CA12 (0.58) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL11756133 | 0.90 | CA12 (0.61) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL10937983 | 0.83 | CA12 (0.57) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL1276727 | 0.78 | ALDH1A1 (0.61) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL9871360 | 0.78 | ALDH1A1 (0.61) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL10937518 | 0.77 | — | — | |
| SCHEMBL3065354 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL9357543 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL23754636 | 0.74 | CA12 (0.78) | ALDH1A1ALDH2CA12CA1CA9 | |
| SCHEMBL712961 | 0.74 | ALDH1A1 (0.56) | ALDH1A1ALDH2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466639-B1 | Lubricant composition | CIBA GEIGY AG (CH) | 1994-08-10 | — | — | EP | disclosed |
| US-5262072-A | Stabilization of a lubricant or hydraulic fluid against oxidation and/or heat degradation | CIBA-GEIGY CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0466639-A1 | Lubricant composition | CIBA-GEIGY AG (CH) | 1992-01-15 | — | — | EP | disclosed |
| US-4545802-A | PYRAZOLINE COMPOUNDS AS NITRIFICATION INHIBITORS OF NITROGEN FERTILIZERS | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | disclosed |
| US-4339455-A | 1-(3-Pyridyl)-2,2,2-trihaloethyl compounds and fungicidal compositions containing the same | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4189486-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-02-19 | — | — | US | disclosed |
| US-4118378-A | THIURAM SULFIDES OF OXAZOLIDINES AND THIAZOLIDINES | PENNWALT CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
| US-4099003-A | NON-BLOOMING ACCELERATOR AND PROCESS FOR VULCANIZATION OF EPDM ELASTOMERS | PENNWALT CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4023957-A | Herbicidal 1-thiadiazolyl-5-carbamoyloxyimidazolidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4001241-A | GASTRIC ACID, ANTISECRETORY AGENTS | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3966945-A | 2-Alkoxy(and 2-alkoxyalkyl)-2-heterocyclic-thioacetamides for inhibiting gastric acid secretion | SMITHKLINE CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
| US-3956494-A | ANTISECRETORY AGENTS, HETEROCYCLIC THIOPROPIONAMIDES | SMITHKLINE CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3948892-A | 2-Alkoxy(and 2-amino)-3-amino-2-heterocyclic-thiopropanamides | SMITHKLINE CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |