Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396336 | 0.96 | PRCP (0.59) | PRCPTLR2HTR2CHTR2BKDM4E | |
| Fumaric Acid SCHEMBL9344920 | 0.85 | PRCP (0.46) | PRCPTLR2HTR2CHTR2BKDM4E | |
| SCHEMBL9330739 | 0.81 | BCHE (0.38) | PRCP | |
| SCHEMBL9799548 | 0.80 | PRCP (0.41) | PRCPTLR2HTR2C | |
| SCHEMBL3403308 | 0.78 | CA12 (0.36) | PRCPTLR2DPP7 | |
| SCHEMBL3307245 | 0.78 | PRCP (0.34) | PRCPTLR2DPP7 | |
| SCHEMBL3305980 | 0.78 | CA12 (0.36) | PRCPTLR2DPP7 | |
| SCHEMBL4430690 | 0.78 | PRCP (0.34) | PRCPTLR2DPP7 | |
| SCHEMBL15329272 | 0.77 | PRCP (0.70) | PRCPTLR2HTR2CHTR2BKDM4E | |
| Hydrochloric Acid SCHEMBL3308857 | 0.77 | CA12 (0.36) | PRCPTLR2DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |