Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345022 | 0.82 | POLB (0.38) | SMN1; SMN2KMT2APOLB | |
| SCHEMBL9344131 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2APOLBTSHR | |
| SCHEMBL9348697 | 0.80 | PRCP (0.57) | PRCPTLR2HTR2C | |
| SCHEMBL13396336 | 0.77 | PRCP (0.59) | PRCPTLR2HDAC8HTR2C | |
| Fumaric Acid SCHEMBL9344148 | 0.69 | FKBP1A (0.35) | SMN1; SMN2KMT2APOLBTSHR | |
| Fumaric Acid SCHEMBL9344920 | 0.68 | PRCP (0.46) | PRCPTLR2SMN1; SMN2KMT2AHTR2C | |
| SCHEMBL9329979 | 0.67 | THRB (0.30) | — | |
| SCHEMBL9332542 | 0.67 | BCHE (0.37) | SMN1; SMN2KMT2APOLB | |
| SCHEMBL9346142 | 0.65 | POLB (0.39) | SMN1; SMN2KMT2APOLBTSHR | |
| SCHEMBL9330739 | 0.65 | BCHE (0.38) | PRCPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |