SCHEMBL9350132

SCHEMBL9350132

CC[C@H]1CC[C@@H](C2CCC(c3cc(C)c(Oc4ccc(N)cc4)c(C)c3)(c3cc(C)c(Oc4ccc(N)cc4)c(C)c3)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TEAD4 Q15561 1/20 0.33
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352388 1.00 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9350138 1.00 ALDH1A1 (0.34) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9350703 0.93 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9350060 0.92 NFE2L2 (0.33) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9348622 0.92 NFE2L2 (0.33) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9348615 0.92 NFE2L2 (0.33) ALDH1A1SMN1; SMN2TEAD4MAPTTDP1
SCHEMBL9352472 0.90 NFE2L2 (0.32) ALDH1A1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL9348768 0.90 NFE2L2 (0.32) ALDH1A1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL9348761 0.90 NFE2L2 (0.32) ALDH1A1SMN1; SMN2MAPTNPC1RAB9A
SCHEMBL9352200 0.89 NFE2L2 (0.31) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389092-B1 Liquid crystal-aligning coating and liquid crystal element CHISSO CORP (JP) 1994-09-07 EP disclosed
US-5152918-A Cyclohexyl aromatic polyimides; controlling pretilt angle CHISSO CORPORATION (JP) 1992-10-06 US disclosed