Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348957 | 0.93 | GPBAR1 (0.47) | PLK1SCN5ASCN2AKDM4ENPC1 | |
| SCHEMBL7607605 | 0.87 | PLK1 (0.47) | PLK1SCN5ASCN2AKDM4ENPC1 | |
| SCHEMBL9350160 | 0.85 | PLK1 (0.47) | PLK1SCN5ASCN2AKDM4ENPC1 | |
| SCHEMBL7605909 | 0.82 | GPBAR1 (0.46) | RAB9AGPBAR1ALDH1A1 | |
| SCHEMBL9348628 | 0.81 | ITGB1 (0.42) | LMNAHPGDALDH1A1ITGB1 | |
| SCHEMBL9348899 | 0.80 | POLB (0.51) | SCN5ASCN2AKDM4EGPBAR1LMNA | |
| SCHEMBL9350203 | 0.80 | ALDH1A1 (0.42) | PLK1SCN5ASCN2AKDM4ENPC1 | |
| SCHEMBL7607640 | 0.79 | GPBAR1 (0.44) | RAB9AGPBAR1HPGDALDH1A1 | |
| SCHEMBL9348699 | 0.78 | GPBAR1 (0.45) | KDM4ENPC1RAB9AGPBAR1LMNA | |
| SCHEMBL9350210 | 0.78 | NPC1 (0.40) | KDM4ENPC1RAB9AGPBAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |