SCHEMBL9350244

SCHEMBL9350244

O=C(c1ccccc1)C(CO)CO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
MAPK1 P28482 3/20 0.53
HTT P42858 2/20 0.53
RAB9A P51151 2/20 0.53
ATM Q13315 2/20 0.53
NPC1 O15118 1/20 0.53
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MDM2 Q00987 1/20 0.52
CES1 P23141 4/20 0.50
CES2 O00748 3/20 0.50
LMNA P02545 2/20 0.50
TSHR P16473 3/20 0.48
ALKBH5 Q6P6C2 1/20 0.47
PGR P06401 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
HTR2A P28223 1/20 0.47
HRH1 P35367 1/20 0.47
KCNH2 Q12809 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6054597 0.87 MMP2 (0.53) MAPTMAPK1HTTRAB9AATM
SCHEMBL27863805 0.87 MAPT (0.51) MAPTMAPK1HTTRAB9AATM
SCHEMBL16466619 0.84 RAB9A (0.53) MAPTMAPK1HTTRAB9AATM
SCHEMBL18658529 0.82 RAB9A (0.60) MAPTMAPK1HTTRAB9AATM
SCHEMBL3736563 0.82 RAB9A (0.44) MAPTMAPK1HTTRAB9AATM
SCHEMBL6386448 0.81 MDM2 (0.63) MAPTMAPK1HTTRAB9AATM
SCHEMBL760303 0.79 MAPK1 (0.52) MAPTMAPK1HTTRAB9AATM
SCHEMBL2985359 0.79 CES1 (0.54) MAPTMAPK1HTTRAB9AATM
SCHEMBL1629814 0.79 MMP2 (0.57) MAPTMAPK1HTTRAB9AATM
SCHEMBL11531382 0.79 MAPT (0.52) MAPTMAPK1HTTRAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096858-A1 COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed
CN-111533961-A Rubber composition for tire and pneumatic tire 住友橡胶工业株式会社 2020-08-14 CN disclosed
WO-2020132792-A1 2-BENZOYL MALONATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 江苏联化科技有限公司 2020-07-02 WO disclosed
EP-0320227-B1 Method of preventing polymer-scale formation SHINETSU CHEMICAL CO (JP) 1994-09-07 EP disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed
EP-0320227-A2 Method of preventing polymer-scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1989-06-14 EP disclosed