Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.50 |
| ▸ | RXRB | P28702 | 7/20 | 0.50 |
| ▸ | RXRG | P48443 | 7/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | RARG | P13631 | 5/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP26B1 | Q9NR63 | 4/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839029 | 0.82 | RXRA (0.56) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8674842 | 0.75 | RXRA (0.68) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL9360554 | 0.73 | RXRA (0.50) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7720638 | 0.72 | RXRA (0.61) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL1756396 | 0.72 | NR4A2 (0.62) | PPARGMRGPRX4 | |
| SCHEMBL8676840 | 0.70 | RXRB (0.71) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8839079 | 0.70 | CYP26A1 (0.85) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8907781 | 0.70 | MAOB (0.53) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8320121 | 0.70 | RXRA (0.69) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL8675765 | 0.69 | PPARG (0.54) | RXRARXRBRXRGPPARGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552282-B1 | BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS | CIRD GALDERMA (FR) | 1994-08-24 | — | — | EP | disclosed |
| EP-0552282-A1 | BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS. | CIRD GALDERMA (FR) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006948-A1 | BI-AROMATIC COMPOUNDS AND THEIR USE IN HUMAN AND VETERINARY MEDECINE AND IN COSMETIC PREPARATIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (CIRD GALDERMA) (FR) | 1992-04-30 | — | — | WO | disclosed |