Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
| ▸ | AGT | P01019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346802 | 0.90 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL7292232 | 0.86 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9308011 | 0.81 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9350575 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL7283197 | 0.79 | CYP3A4 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9350422 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9663317 | 0.78 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9350518 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9346516 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9350392 | 0.77 | PPARG (0.39) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294620-A | Hypotensive agents or compounds for cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-15 | — | — | US | disclosed |
| US-5217976-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-08 | — | — | US | disclosed |