Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9350467 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7292232 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9308011 | 0.83 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9663926 | 0.83 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9434167 | 0.79 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9350575 | 0.77 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9350422 | 0.77 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9663317 | 0.76 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9499272 | 0.76 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9258720 | 0.76 | AGTR1 (0.45) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294620-A | Hypotensive agents or compounds for cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-15 | — | — | US | disclosed |
| US-5217976-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-08 | — | — | US | disclosed |