Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.58 |
| ▸ | ATP4B | P51164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349290 | 0.88 | ATP4A (0.67) | ATP4AATP4B | |
| SCHEMBL9353380 | 0.85 | KDM4E (0.54) | — | |
| SCHEMBL9349228 | 0.82 | ATP4A (0.58) | ATP4AATP4B | |
| SCHEMBL9349638 | 0.80 | ATP4A (0.70) | ATP4AATP4B | |
| SCHEMBL9353287 | 0.79 | ATP4A (0.69) | ATP4AATP4B | |
| SCHEMBL9349683 | 0.79 | MEN1 (0.55) | — | |
| SCHEMBL9650832 | 0.79 | ATP4A (0.80) | ATP4AATP4B | |
| SCHEMBL9260552 | 0.78 | ATP4A (0.76) | ATP4AATP4B | |
| SCHEMBL20435772 | 0.76 | POLB (0.90) | — | |
| SCHEMBL31087707 | 0.76 | POLB (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416749-B1 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT (NL) | 1994-08-17 | — | — | EP | claimed |
| US-5082841-A | Enzyme inhibitor | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1992-01-21 | — | — | US | claimed |
| EP-0416749-B1 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT (NL) | 1994-08-17 | — | — | EP | disclosed |
| US-5082841-A | Enzyme inhibitor | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1992-01-21 | — | — | US | disclosed |
| EP-0416749-A2 | Substituted 4-aminoquinolines | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-03-13 | — | — | EP | disclosed |