SCHEMBL9350716

SCHEMBL9350716

C=Cc1ccccc1COC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TSHR P16473 2/20 0.31
KMT2A Q03164 1/20 0.31
SLC6A1 P30531 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9674793 0.82 CARM1 (0.33) TSHRKMT2A
SCHEMBL19433042 0.81 KDM4E (0.39) KDM4EL3MBTL1KMT2ASLC6A1
SCHEMBL1639896 0.78 CARM1 (0.41)
SCHEMBL9676528 0.77 TSHR (0.37) L3MBTL1TSHRKMT2A
SCHEMBL9674783 0.75 GAA (0.40) KDM4EL3MBTL1KMT2A
SCHEMBL7935333 0.73 EPHX2 (0.31)
SCHEMBL8838396 0.69 MEN1 (0.39) KDM4EKMT2A
SCHEMBL9350722 0.69 OPRM1 (0.34)
SCHEMBL7476559 0.69 TSHR (0.51) TSHRKMT2A
SCHEMBL9040363 0.68 KDM4E (0.39) KDM4EL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US claimed
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5077340-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5047489-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-09-10 US disclosed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US disclosed