SCHEMBL9350722

SCHEMBL9350722

C=CC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1OCc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.34
OPRL1 P41146 2/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSK P43235 1/20 0.34
TMEM97 Q5BJF2 1/20 0.33
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
PRMT8 Q9NR22 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
DPP4 P27487 1/20 0.32
FKBP1A P62942 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9674804 0.79 BCHE (0.36) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL9676535 0.75 ALDH1A1 (0.38) HTR2C
SCHEMBL1639896 0.73 CARM1 (0.41) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL9350720 0.70 CARM1 (0.32) CARM1PRMT6
SCHEMBL9350716 0.69 KDM4E (0.33)
SCHEMBL9163493 0.69 CRHBP (0.35) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL9674791 0.68 ALDH1A1 (0.42) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL8838264 0.68 MAPK1 (0.38) CHRM2CHRM1CHRM3
SCHEMBL7693739 0.67 CTSL (0.43) OPRM1OPRL1CTSLCTSBCTSK
SCHEMBL7935333 0.67 EPHX2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US claimed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5077340-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5047489-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-09-10 US disclosed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US disclosed