Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251299 | 0.86 | CES1 (0.47) | CES1CYP3A4CYP2D6KCNN4CYP2C19 | |
| SCHEMBL5982853 | 0.85 | CES1 (0.43) | CES1CYP3A4CYP2D6KCNN4CYP2C19 | |
| SCHEMBL6616083 | 0.84 | CES1 (0.40) | CES1CYP3A4CYP2D6KCNN4CYP2C19 | |
| SCHEMBL28521888 | 0.83 | ESR1 (0.44) | CYP3A4LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL36702 | 0.81 | CES1 (0.66) | CES1CYP3A4CYP2D6KCNN4CYP2C19 | |
| SCHEMBL9065321 | 0.81 | CES1 (0.66) | CES1CYP3A4CYP2D6KCNN4CYP2C19 | |
| Acetophenone SCHEMBL27649666 | 0.80 | CES1 (0.58) | CES1CYP3A4CYP2D6LMNASMN1; SMN2 | |
| SCHEMBL2586906 | 0.78 | CES1 (0.66) | CES1CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL5598169 | 0.78 | CES1 (0.75) | CES1CYP3A4CYP2D6KCNN4CYP2C19 | |
| SCHEMBL28641318 | 0.78 | CES1 (0.44) | CES1CYP3A4CYP2D6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969953-A | Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116969952-A | Diphenyl pyrrolo-pyrrole-dione derivative and pigment composition thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116693857-A | Compound containing multifunctional polysiloxane structure and application thereof | 烟台希尔德材料科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-118878472-A | Branched thioether dispersing agent, preparation and application thereof | 山东凯瑞尔光电科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118812566-A | Hyperbranched triazine modified pyrrolopyrrolidone compound as well as preparation method and application thereof | 山东凯瑞尔光电科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118812565-A | Triazine derivative modified halogenated diphenyl pyrrolopyrrole dione compound and preparation method and application thereof | 山东凯瑞尔光电科技有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118530241-A | Thioether substituted diphenyl pyrrolopyrrole diketone and preparation method and application thereof | 山东凯瑞尔光电科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-116969953-A | Diphenyl pyrrolo-pyrrole-dione derivative, pigment composition and application thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116969952-A | Diphenyl pyrrolo-pyrrole-dione derivative and pigment composition thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116693857-A | Compound containing multifunctional polysiloxane structure and application thereof | 烟台希尔德材料科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116693856-A | Adhesive resin and application thereof | 烟台希尔德材料科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-114080390-A | Synthesis of coelenterazine | 国际纸业公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-112368286-A | Synthesis of coelenterazine | 国际纸业公司 | 2021-02-12 | — | — | CN | disclosed |
| EP-2454261-B1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | UNIV SIENA (IT) | 2014-11-19 | — | — | EP | disclosed |
| US-8546147-B2 | Imidazo[1,2-α]pyrazin-3(7H)-one derivatives bearing a new electron-rich structure | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2013-10-01 | — | — | US | disclosed |
| US-20120171703-A1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | UNIVERSITÁ DEGLI STUDI DI SIENA (IT) | 2012-07-05 | — | — | US | disclosed |
| EP-2454261-A1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | Universita Degli Studi di Siena (IT) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007314-A1 | IMIDAZO[1,2-α]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171703-A1 | IMIDAZO[1,2-ALPHA]PYRAZIN-3(7H)-ONE DERIVATIVES BEARING A NEW ELECTRON-RICH STRUCTURE | GLB1, NDUFV1, IK | CES1 601/4885CYP3A4 257/4885CYP2D6 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.