SCHEMBL9350745

SCHEMBL9350745

C=CC(=O)NC1CC(C)(C)N(OC2CCCCC2)C(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.34
TEAD1 P28347 4/20 0.33
EPHX1 P07099 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
JAK3 P52333 5/20 0.31
TSHR P16473 1/20 0.31
TGM2 P21980 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7470309 0.83 ALDH1A1 (0.38) EPHX2EPHX1GAASMN1; SMN2HPGD
SCHEMBL13412664 0.82 NPSR1 (0.41) EPHX2EPHX1GAASMN1; SMN2HPGD
SCHEMBL7476001 0.81 GAA (0.45) EPHX2EPHX1GAASMN1; SMN2HPGD
SCHEMBL19424075 0.80 TEAD1 (0.33) TEAD1GAASMN1; SMN2TSHRTGM2
SCHEMBL9041186 0.80 SMN1; SMN2 (0.36) EPHX2EPHX1NPC1SMN1; SMN2HPGD
SCHEMBL9381217 0.78 NPSR1 (0.38) EPHX2EPHX1GAASMN1; SMN2HPGD
SCHEMBL9350731 0.78 TSHR (0.34) EPHX1TSHR
SCHEMBL25701770 0.77 SMN1; SMN2 (0.37) TEAD1GAASMN1; SMN2TSHR
SCHEMBL9041095 0.76 ALDH1A1 (0.54) EPHX2EPHX1GAASMN1; SMN2HPGD
SCHEMBL16501810 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP claimed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US claimed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP claimed
EP-0389420-B1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5077340-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
US-5047489-A Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY CORPORATION (US) 1991-09-10 US disclosed
US-4983737-A LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES CIBA-GEIGY CORPORATION (US) 1991-01-08 US disclosed
EP-0389420-A1 Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed