Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041095 | 0.95 | ALDH1A1 (0.54) | GAAALDH1A1EPHX2SMN1; SMN2HPGD | |
| SCHEMBL13412664 | 0.93 | NPSR1 (0.41) | GAAALDH1A1EPHX2SMN1; SMN2HPGD | |
| SCHEMBL9381217 | 0.89 | NPSR1 (0.38) | GAAALDH1A1EPHX2SMN1; SMN2HPGD | |
| SCHEMBL7470309 | 0.85 | ALDH1A1 (0.38) | GAAALDH1A1EPHX2SMN1; SMN2HPGD | |
| SCHEMBL9350819 | 0.82 | GAA (0.37) | GAAALDH1A1EPHX2HPGDSIGMAR1 | |
| SCHEMBL9350824 | 0.82 | GAA (0.37) | GAAALDH1A1EPHX2HPGDSIGMAR1 | |
| SCHEMBL9041186 | 0.82 | SMN1; SMN2 (0.36) | EPHX2SMN1; SMN2HPGDNPSR1MAPT | |
| SCHEMBL9350745 | 0.81 | EPHX2 (0.34) | GAAEPHX2SMN1; SMN2HPGDNPSR1 | |
| SCHEMBL9040026 | 0.79 | SMN1; SMN2 (0.43) | GAAALDH1A1EPHX2SMN1; SMN2MAPT | |
| SCHEMBL16501810 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |