Thiram

Thiram

SCHEMBL9350807

CCCSSCCC.CN(C)C(=S)SSC(=S)N(C)C

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 8/20 0.62
ALDH1A1 P00352 7/20 0.62
ALDH2 P05091 5/20 0.62
LMNA P02545 3/20 0.62
HTT P42858 3/20 0.62
FAAH O00519 3/20 0.62
TP53 P04637 2/20 0.62
HSP90AA1 P07900 2/20 0.62
CYP3A4 P08684 2/20 0.62
FBP1 P09467 2/20 0.62
MAPT P10636 2/20 0.62
PKM P14618 2/20 0.62
HPGD P15428 2/20 0.62
ALOX15 P16050 2/20 0.62
ALOX12 P18054 2/20 0.62
LOX P28300 2/20 0.62
LOXL3 P58215 2/20 0.62
KMT2A Q03164 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
LOXL4 Q96JB6 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiram SCHEMBL9351017 0.86 ALDH1A1 (0.56) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL9351008 0.86 ALDH1A1 (0.62) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL20473180 0.83 ALDH1A1 (0.52) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL22471732 0.83 ALDH1A1 (0.52) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL9246528 0.81 ALDH1A1 (0.50) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL3685998 0.80 ALDH1A1 (0.68) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL28087731 0.79 ALDH1A1 (0.77) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL21144 0.79 ALDH1A1 (1.00) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL1216571 0.79 ALDH1A1 (1.00) MGLLALDH1A1ALDH2LMNAHTT
Thiram SCHEMBL9350849 0.77 ALDH1A1 (0.56) MGLLALDH1A1ALDH2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504320-B1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES UNIROYAL CHEM CO INC (US) 1994-09-21 EP disclosed
US-5254709-A Catalytic reaction of phosphorus trihalide with a phenolic compound UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-19 US disclosed
EP-0504320-A1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES. UNIROYAL CHEM CO INC (US) 1992-09-23 EP disclosed
WO-1991009040-A1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES UNIROYAL CHEMICAL COMPANY, INC. (US) 1991-06-27 WO disclosed