Thiram

Thiram

SCHEMBL22471732

CCCCCCCCCSSCCCCCCCCC.CN(C)C(=S)SSC(=S)N(C)C

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
MGLL Q99685 4/20 0.52
ALDH2 P05091 4/20 0.52
LMNA P02545 4/20 0.52
HTT P42858 3/20 0.52
TP53 P04637 3/20 0.52
MAPT P10636 3/20 0.52
HSD17B10 Q99714 3/20 0.52
HSP90AA1 P07900 2/20 0.52
CYP3A4 P08684 2/20 0.52
FBP1 P09467 2/20 0.52
PKM P14618 2/20 0.52
HPGD P15428 2/20 0.52
ALOX15 P16050 2/20 0.52
ALOX12 P18054 2/20 0.52
LOX P28300 2/20 0.52
LOXL3 P58215 2/20 0.52
KMT2A Q03164 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
LOXL4 Q96JB6 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiram SCHEMBL20473180 1.00 ALDH1A1 (0.52) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL9246528 0.98 ALDH1A1 (0.50) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL9351017 0.92 ALDH1A1 (0.56) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL20473181 0.88 ALDH1A1 (0.52) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL9314198 0.86 ALDH1A1 (0.54) ALDH1A1MGLLALDH2LMNAHTT
SCHEMBL5933979 0.83 ALDH1A1 (0.50) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL9350807 0.83 MGLL (0.62) ALDH1A1MGLLALDH2LMNAHTT
SCHEMBL11831162 0.83 ALDH1A1 (0.55) ALDH1A1MGLLALDH2LMNAHTT
SCHEMBL11826537 0.83 ALDH1A1 (0.55) ALDH1A1MGLLALDH2LMNAHTT
SCHEMBL11832756 0.83 ALDH1A1 (0.55) ALDH1A1MGLLALDH2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020195492-A1 SEALANT RUBBER COMPOSITION FOR INNER TIRE SURFACE AND SEALANT-COATED TIRE 住友ゴム工業株式会社 2020-10-01 WO disclosed