Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040343 | 0.88 | ALDH1A1 (0.43) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL9315240 | 0.81 | HPGD (0.61) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL10506799 | 0.80 | CDK1 (0.51) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL10506586 | 0.79 | ALDH1A1 (0.59) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL13684403 | 0.78 | CDK1 (0.54) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL4043989 | 0.77 | CDK1 (0.56) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL10506918 | 0.77 | CDK1 (0.48) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3276252 | 0.77 | KDM4E (0.57) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL5356682 | 0.76 | CDK1 (0.55) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL4039439 | 0.75 | ALOX15 (0.60) | ALDH1A1RAB9AKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | claimed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | claimed |
| EP-0428442-B1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | OREAL (FR) | 1994-08-31 | — | — | EP | disclosed |
| EP-0428442-A1 | Composition comprising derivatives of 6- or 7-hydroxyindole as couplers and dyeing processes using same | L'OREAL (FR) | 1991-05-22 | — | — | EP | disclosed |