Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 12/20 | 0.45 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | INPP5B | P32019 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504804 | 0.83 | INPPL1 (0.48) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL9350981 | 0.83 | GAA (0.44) | GAAMAPTTSHR | |
| SCHEMBL27525487 | 0.81 | INPPL1 (0.47) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL9560188 | 0.78 | THRB (0.35) | GAAMAPT | |
| SCHEMBL9347214 | 0.75 | INPPL1 (0.45) | INPPL1INPP5AAKT1INPP5BGAA | |
| SCHEMBL9417194 | 0.75 | INPPL1 (0.41) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL9765444 | 0.74 | INPPL1 (0.59) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL28075579 | 0.71 | INPPL1 (0.68) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL28422378 | 0.70 | INPPL1 (0.65) | INPPL1INPP5AAKT1INPP5BSRC | |
| SCHEMBL1901599 | 0.70 | HSD17B10 (0.41) | INPPL1INPP5AAKT1INPP5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317243-B1 | Method and test composition for determination of enzyme activity | KYOWA MEDEX CO LTD (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0317243-A2 | Method and test composition for determination of enzyme activity | Kyowa Medex Co. Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |