SCHEMBL9350995

SCHEMBL9350995

CC1(C)CC(N(C(=O)C(=O)N(C2CC(C)(C)NC(C)(C)C2)C2CC(C)(C)NC(C)(C)C2)C2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
GAA P10253 2/20 0.36
POLB P06746 2/20 0.35
RECQL P46063 1/20 0.34
EZH2 Q15910 2/20 0.33
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
ATM Q13315 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4459766 0.88 ALOX15 (0.37) ALOX15GAAPOLBRECQL
SCHEMBL8340480 0.83 ALOX15 (0.35) ALOX15GAAPOLBRECQLEZH2
SCHEMBL11547014 0.81 GAA (0.38) ALOX15GAAPOLBRECQLEZH2
SCHEMBL11099842 0.81 ALOX15 (0.41) ALOX15GAAPOLBRECQLEZH2
SCHEMBL9355007 0.81 GAA (0.38) ALOX15GAAPOLBRECQLEZH2
SCHEMBL3680294 0.78 ALOX15 (0.36) ALOX15GAAPOLBRECQL
SCHEMBL28406644 0.77 GAA (0.39) ALOX15GAAPOLBRECQLEZH2
SCHEMBL9354706 0.77 GAA (0.36) ALOX15GAAPOLBHTT
SCHEMBL11547009 0.77 ALOX15 (0.38) ALOX15GAAPOLBRECQLEZH2
SCHEMBL11099845 0.76 ALOX15 (0.50) ALOX15GAAPOLBRECQLEZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 EP disclosed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 US disclosed