SCHEMBL8340480

SCHEMBL8340480

CC1(C)CC(N(C(=O)C(=O)NN)C2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
POLB P06746 2/20 0.33
GAA P10253 3/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
EZH2 Q15910 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTT P42858 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9350995 0.83 ALOX15 (0.41) ALOX15POLBGAARECQLALDH1A1
SCHEMBL4459766 0.80 ALOX15 (0.37) ALOX15POLBGAARECQLKMT2A
SCHEMBL8336234 0.76 L3MBTL1 (0.32) L3MBTL1
SCHEMBL11547014 0.74 GAA (0.38) ALOX15POLBGAARECQLKMT2A
SCHEMBL2956173 0.71 GAA (0.50) POLBGAARECQLKMT2AALDH1A1
SCHEMBL10557784 0.71 GAA (0.37) ALOX15POLBGAARECQLKMT2A
SCHEMBL9355007 0.71 GAA (0.38) ALOX15POLBGAARECQLKMT2A
SCHEMBL11099842 0.71 ALOX15 (0.41) ALOX15POLBGAARECQLALDH1A1
SCHEMBL11547009 0.70 ALOX15 (0.38) ALOX15POLBGAARECQLKMT2A
SCHEMBL11299640 0.69 RECQL (0.42) POLBGAARECQLKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9238609-B2 Dicarboxylic acid monomers and methods of making and using the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-19 US disclosed
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed
US-20150322200-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 US disclosed
WO-2015171709-A1 AMORPHOUS POLYESTER COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-12 WO disclosed
US-8633265-B2 UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-21 US disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 WO disclosed
US-20120184651-A1 UV Stabilization of Isosorbide Polycarbonates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-07-19 US disclosed
US-5981065-A ELECTRICAL CONDUCTORS HAVING GREASE FILLED INTERSTICES THEREBETWEEN, EACH ELECTRICAL CONDUCTOR COVERING WITH POLYOLEFINS LAYER AND THE REACTION PRODUCT OF A HINDERED AMINE AMIC ACID HYDRAZIDE, A PHENOL OR AN AMINE HYDRAZIDE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-11-09 US disclosed
EP-0303279-B1 Reactive hindered amine light stabilizers ATOCHEM NORTH AMERICA ELF (US) 1996-09-25 EP disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4975489-A Heating an anhydride-containing polymer with a hydrazine derivative of a 2,2,6,6-tetramethyl-4-aminopiperidine in an inert solvent of by melt blending ATOCHEM NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
WO-1990009408-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
US-4857595-A Polymer bound hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-08-15 US disclosed
US-4824884-A Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers PENNWALT CORPORATION (US) 1989-04-25 US disclosed
EP-0303987-A2 Polymer bound hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303279-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
EP-0303282-A2 Cyclic anhydride derivatives of hydrazide functionalized hindered amine light stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336869-A1 DICARBOXYLIC ACID MONOMERS AND METHODS OF MAKING AND USING THE SAME PGD, CDA, PPIA ALOX15 1081/4885POLB 937/4885GAA 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.