Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630544 | 0.78 | CYP1A2 (0.38) | GAAMAPTCYP1A2MEN1KMT2A | |
| SCHEMBL8630384 | 0.77 | CYP1A2 (0.37) | GAAMAPTCYP1A2MEN1KMT2A | |
| SCHEMBL8375636 | 0.75 | MAOA (0.51) | GRM2HRH3MAOAMAOB | |
| SCHEMBL9352573 | 0.75 | OPRL1 (0.41) | GRM2DRD2DRD3CHRM4GAA | |
| SCHEMBL5676928 | 0.75 | OPRL1 (0.41) | GRM2DRD2DRD3CHRM4GAA | |
| SCHEMBL19641604 | 0.74 | GAA (0.34) | SLC6A2SLC6A4GAA | |
| SCHEMBL8630399 | 0.73 | CYP1A2 (0.42) | GAAMAPTCYP1A2MEN1KMT2A | |
| SCHEMBL9251351 | 0.73 | MEN1 (0.39) | GRM2DRD2DRD3CHRM2CHRM4 | |
| SCHEMBL9251341 | 0.73 | MEN1 (0.39) | GRM2DRD2DRD3CHRM2CHRM4 | |
| SCHEMBL9248396 | 0.73 | OPRL1 (0.46) | GRM2SLC6A2SLC6A4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318721-A | Nematic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-07 | — | — | US | disclosed |
| US-4871469-A | TRIFLUOROTOLUENE DERIVATIVES | BESCRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |