Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10597454 | 0.81 | ALDH1A1 (0.78) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL28379897 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL30003256 | 0.81 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL23271684 | 0.81 | ALDH1A1 (0.60) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL5189237 | 0.81 | CA2 (0.46) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL11170890 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL17720798 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL28381116 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL9186771 | 0.79 | ELANE (0.52) | ALDH1A1CYP3A4LMNATSHRMAPK1 | |
| SCHEMBL9352810 | 0.79 | ELANE (0.52) | ALDH1A1CYP3A4LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402339-B1 | Improved process for the production of carbonate esters | MONSANTO CO (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5252770-A | Process for the production of carbonate esters | MONSANTO COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0402339-A1 | Improved process for the production of carbonate esters | MONSANTO COMPANY (US) | 1990-12-12 | — | — | EP | disclosed |