SCHEMBL9352009

SCHEMBL9352009

COc1ccc(Nc2nc(Nc3ccc(OC)cc3)c3ncnc(Nc4ccc(OC)cc4)c3n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 2/20 0.55
SYK P43405 1/20 0.55
NPY5R Q15761 1/20 0.52
MAPT P10636 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
GAA P10253 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
GRM1 Q13255 1/20 0.51
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
CLK1 P49759 2/20 0.50
PDE4B Q07343 1/20 0.50
PDE4D Q08499 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351742 0.89 MAPT (0.62) AURKASYKNPY5RMAPTSMN1; SMN2
SCHEMBL30683210 0.81 PDPK1 (0.59) MAPTSMN1; SMN2MEN1KMT2AGAA
SCHEMBL7939982 0.81 KDR (0.50) AURKANPY5RMEN1KMT2AL3MBTL1
SCHEMBL7937469 0.80 EGFR (0.55) AURKASYKNPY5RMAPTMEN1
SCHEMBL9550840 0.79 AURKA (0.64) AURKASYKNPY5RMAPTSMN1; SMN2
SCHEMBL11812041 0.76 MAPT (0.81) AURKASYKNPY5RMAPTSMN1; SMN2
SCHEMBL4913780 0.72 TTBK1 (0.62) MAPTSMN1; SMN2MEN1KMT2AGRM1
SCHEMBL29309559 0.72 MAPT (0.56) MAPTSMN1; SMN2MEN1KMT2AGRM1
SCHEMBL9206939 0.71 EGFR (0.66) MAPTSMN1; SMN2MEN1KMT2AGRM1
SCHEMBL8320082 0.71 EGFR (0.56) AURKASYKMAPTSMN1; SMN2GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5346772-A HAVING A HIGH LUMINANCE AND HIGH EMISSION EFFICIENCY PIONEER ELECTRONIC CORPORATION (JP) 1994-09-13 US claimed
US-5346772-A HAVING A HIGH LUMINANCE AND HIGH EMISSION EFFICIENCY PIONEER ELECTRONIC CORPORATION (JP) 1994-09-13 US disclosed
EP-0583861-A1 Organic electroluminescene device PIONEER ELECTRONIC CORPORATION (JP) 1994-02-23 EP disclosed