Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893027 | 0.82 | TDP1 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL14513819 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1 | |
| SCHEMBL9734057 | 0.82 | — | — | |
| SCHEMBL10807828 | 0.80 | USP2 (0.54) | — | |
| SCHEMBL5014524 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL2233813 | 0.73 | TDP1 (0.42) | ALDH1A1TDP1 | |
| SCHEMBL8840629 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TDP1 | |
| SCHEMBL24759469 | 0.73 | — | — | |
| SCHEMBL27595330 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL13039797 | 0.70 | ALDH1A1 (0.43) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375349-B1 | Phosphinic acid substituted steroids as inhibitors of steroid 5alpha-reductase | SMITHKLINE BEECHAM CORP (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0375351-B1 | Phosphonic acid substituted steroids as steroid 5alpha-reductase inhibitors | SMITHKLINE BEECHAM CORP (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5026882-A | Phosphinic acid substituted steroids as inhibitors of steroid 5α-reductase | SMITHKLINE BEECHAM CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| US-4946834-A | ACRYLATE ANALOGUES OF STEROIDAL SYNTHETIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |
| EP-0375351-A1 | Phosphonic acid substituted steroids as steroid 5alpha-reductase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0375349-A1 | Phosphinic acid substituted steroids as inhibitors of steroid 5alpha-reductase | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-27 | — | — | EP | disclosed |