Thiram

Thiram

SCHEMBL9352185

CN(C)C(=S)SSC(=S)N(C)C.c1ccc(CSCc2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.58
ALDH1A1 P00352 6/20 0.50
FAAH O00519 2/20 0.48
PHGDH O43175 1/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
MAPT P10636 2/20 0.48
HTT P42858 2/20 0.48
KDM4E B2RXH2 1/20 0.48
JAK2 O60674 1/20 0.48
BBOX1 O75936 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
ALDH2 P05091 1/20 0.48
HSP90AA1 P07900 1/20 0.48
CYP3A4 P08684 1/20 0.48
FBP1 P09467 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dibenzyl Disulfide SCHEMBL9351030 0.89 MGLL (0.58) MGLLALDH1A1FAAHPHGDHMEN1
SCHEMBL1158069 0.81 CA12 (0.55) MGLLALDH1A1FAAHPHGDHMEN1
SCHEMBL17966398 0.80 MGLL (0.89) MGLLALDH1A1FAAHPHGDHMEN1
Thiram SCHEMBL9732905 0.78 ALDH1A1 (0.59) MGLLALDH1A1FAAHPHGDHMEN1
Methyl Alcohol SCHEMBL29261078 0.77 CYP2C19 (0.56) ALDH1A1MAPTKDM4ELMNATP53
Thiram SCHEMBL10947679 0.76 ALDH1A1 (0.50) MGLLALDH1A1FAAHPHGDHMEN1
Thiram SCHEMBL5075880 0.75 ALDH1A1 (0.77) MGLLALDH1A1FAAHPHGDHMEN1
Thiram SCHEMBL10880058 0.75 MGLL (0.54) MGLLALDH1A1FAAHPHGDHMEN1
SCHEMBL11818858 0.75 ALDH1A1 (0.48) MGLLALDH1A1FAAHPHGDHMEN1
SCHEMBL206 0.74 CYP2C19 (0.56) KDM4ECYP3A4SMN1; SMN2HSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3091501-A None JP disclosed
CN-114381054-B Synthetic polyisoprene latex condom with reduced nitrosamine content 泰日橡胶工业股份有限公司 2024-04-02 CN disclosed
CN-102164516-B Dip-formed synthetic polyisoprene latex articles with improved intraparticle and interparticle crosslinks ANSELL HEALTHCARE PROD LLC 2013-10-23 CN disclosed
CN-102164516-A Dip-formed synthetic polyisoprene latex articles with improved intraparticle and interparticle crosslinks ANSELL HEALTHCARE PROD LLC 2011-08-24 CN disclosed
EP-0504320-B1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES UNIROYAL CHEM CO INC (US) 1994-09-21 EP disclosed
US-5254635-A Sulfur-free vulcanization ROBINSON BROTHERS LIMITED (GB) 1993-10-19 US disclosed
US-5254709-A Catalytic reaction of phosphorus trihalide with a phenolic compound UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-19 US disclosed
EP-0504320-A1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES. UNIROYAL CHEM CO INC (US) 1992-09-23 EP disclosed
WO-1991009040-A1 METHOD FOR PREPARING STERICALLY HINDERED ARYL PHOSPHITES UNIROYAL CHEMICAL COMPANY, INC. (US) 1991-06-27 WO disclosed
JP-H0391501-A RUBBER PRODUCT AND CURING SYSTEM ROBINSON BROS LTD 1991-04-17 JP disclosed