SCHEMBL935284

SCHEMBL935284

COC(CNN1CCNCC1)OC

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.42
GNAO1 P09471 2/20 0.42
GNAI1 P63096 2/20 0.42
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935161 0.81 GNAI3 (0.43) GNAI3GNAO1GNAI1
SCHEMBL936005 0.76 HTR4 (0.34)
SCHEMBL3707782 0.72 GNAI3 (0.39) GNAI3GNAO1GNAI1
SCHEMBL1537342 0.69
SCHEMBL11264176 0.68 SMN1; SMN2 (0.46) CHRM5CHRM3
SCHEMBL935505 0.68 GNAI3 (0.42) GNAI3GNAO1GNAI1
Bromide SCHEMBL28768421 0.67 GNAI3 (0.53) GNAI3GNAO1GNAI1CHRM5CHRM3
Fluoride SCHEMBL27708727 0.67 GNAI3 (0.53) GNAI3GNAO1GNAI1CHRM5CHRM3
SCHEMBL19629003 0.67 GNAI3 (0.48) GNAI3GNAO1GNAI1CHRM5CHRM3
Hydrochloric Acid SCHEMBL6096892 0.67 GNAI3 (0.59) GNAI3GNAO1GNAI1CHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011006808-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2011-01-20 WO disclosed