Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443484 | 0.84 | GAA (0.58) | EPHX2GAAMAOAMAOBTAS2R38 | |
| SCHEMBL3071122 | 0.81 | HSD17B10 (0.64) | EPHX2GAAMAOAMAOBTAS2R38 | |
| SCHEMBL3067216 | 0.79 | MAPT (0.61) | GAAMAOAMAOBTAS2R38HSD17B10 | |
| SCHEMBL1059890 | 0.77 | KMT2A (0.56) | EPHX2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL28367376 | 0.76 | HSD17B10 (0.56) | EPHX2GAAMAOAMAOBTAS2R38 | |
| SCHEMBL3651334 | 0.76 | TAS2R38 (0.58) | GAATAS2R38HSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL8325341 | 0.76 | ALDH1A1 (0.45) | GAAALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL29875498 | 0.76 | HSD17B10 (0.56) | EPHX2GAAMAOAMAOBTAS2R38 | |
| SCHEMBL7362194 | 0.76 | HSD17B10 (0.58) | EPHX2GAAMAOAMAOBTAS2R38 | |
| SCHEMBL3069527 | 0.76 | ALDH1A1 (0.64) | GAAMAOAMAOBTAS2R38HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4234357-A | — | — | None | — | — | JP | disclosed |
| EP-0469888-B1 | Amidobenzenes | ICI PLC (GB) | 1994-09-28 | — | — | EP | disclosed |
| US-5250570-A | Aldose reductase inhibitors for controlling side effects of diabetes and galactosemia | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-05 | — | — | US | disclosed |
| JP-H04234357-A | AMIDOBENZENES | IMPERIAL CHEM IND PLC <ICI> | 1992-08-24 | — | — | JP | disclosed |
| EP-0469888-A1 | Amidobenzenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-3939184-A | Production of carbonyl compounds substituted in α-position | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |