⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188013 | 0.82 | — | — | |
| SCHEMBL11251614 | 0.80 | — | — | |
| SCHEMBL28072446 | 0.80 | — | — | |
| SCHEMBL4547131 | 0.78 | — | — | |
| SCHEMBL199578 | 0.78 | — | — | |
| SCHEMBL29173713 | 0.77 | — | — | |
| SCHEMBL13102747 | 0.76 | — | — | |
| SCHEMBL22930967 | 0.76 | — | — | |
| SCHEMBL197462 | 0.76 | — | — | |
| SCHEMBL3655509 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014043272-A1 | TRICYCLIC GYRASE INHIBITORS FOR USE AS ANTIBACTERIAL AGENTS | TRIUS THERAPEUTICS INC. (US) | 2014-03-20 | — | — | WO | disclosed |
| EP-0388991-B1 | Fuel compositions | LUBRIZOL CORP (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0388991-A1 | Fuel compositions | The Lubrizol Corporation (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4780111-A | Fuel compositions | THE LUBRIZOL CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0244476-A1 | FUEL COMPOSITIONS. | LUBRIZOL CORP (US) | 1987-11-11 | — | — | EP | disclosed |
| WO-1987003003-A1 | FUEL COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1987-05-21 | — | — | WO | disclosed |