Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354145 | 1.00 | THRB (0.60) | THRBEPHX2RAB9AKMT2ANPC1 | |
| SCHEMBL9354154 | 1.00 | THRB (0.60) | THRBEPHX2RAB9AKMT2ANPC1 | |
| SCHEMBL601098 | 0.84 | EPHX2 (0.61) | EPHX2RAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL601097 | 0.84 | EPHX2 (0.61) | EPHX2RAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL4740680 | 0.76 | CYP3A4 (0.51) | EPHX2RAB9ANPC1EPHX1CYP3A4 | |
| SCHEMBL3856454 | 0.76 | CYP3A4 (0.51) | EPHX2RAB9ANPC1EPHX1CYP3A4 | |
| SCHEMBL4743549 | 0.74 | CYP3A4 (0.53) | EPHX2RAB9ANPC1CYP3A4 | |
| SCHEMBL3191512 | 0.73 | CYP3A4 (0.56) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL3397254 | 0.73 | EPHX2 (1.00) | EPHX2RAB9AKMT2ANPC1ALDH1A1 | |
| SCHEMBL5051924 | 0.73 | EPHX2 (1.00) | EPHX2RAB9AKMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6107613-A | — | — | None | — | — | JP | disclosed |
| JP-H06107613-A | NEW SUCCINIC ACID DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1994-04-19 | — | — | JP | disclosed |