SCHEMBL601098

SCHEMBL601098

COc1ccc(C=C(CC(=O)NC2CCCCC2)C(=O)O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.61
MAPT P10636 1/20 0.57
RAB9A P51151 3/20 0.57
CYP1A2 P05177 3/20 0.56
CYP3A4 P08684 3/20 0.56
CYP2C19 P33261 3/20 0.56
CYP2C9 P11712 2/20 0.56
RECQL P46063 1/20 0.56
CYP2D6 P10635 1/20 0.55
HPGD P15428 1/20 0.55
POLB P06746 3/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
NPC1 O15118 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
EPHX1 P07099 1/20 0.51
ALDH1A1 P00352 4/20 0.51
USP2 O75604 1/20 0.51
HTT P42858 1/20 0.51
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL601097 1.00 EPHX2 (0.61) EPHX2MAPTRAB9ACYP1A2CYP3A4
SCHEMBL9354154 0.84 THRB (0.60) EPHX2MAPTRAB9ACYP3A4CYP2C19
SCHEMBL9354151 0.84 THRB (0.60) EPHX2MAPTRAB9ACYP3A4CYP2C19
SCHEMBL9354145 0.84 THRB (0.60) EPHX2MAPTRAB9ACYP3A4CYP2C19
SCHEMBL28505254 0.82 EPHX2 (0.47) EPHX2MAPTRAB9ACYP1A2CYP3A4
SCHEMBL6654010 0.77 GSK3B (0.51) MAPTRAB9ACYP1A2RECQLHPGD
SCHEMBL6654014 0.77 GSK3B (0.51) MAPTRAB9ACYP1A2RECQLHPGD
SCHEMBL9050821 0.76 HPGD (0.42) MAPTRAB9AHPGDKMT2ANPC1
SCHEMBL9050826 0.76 HPGD (0.42) MAPTRAB9AHPGDKMT2ANPC1
SCHEMBL9050824 0.76 HPGD (0.42) MAPTRAB9AHPGDKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 US disclosed
US-10428220-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-01 US disclosed
EP-3233944-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-09-04 EP disclosed
EP-2393849-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
EP-3234042-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
EP-2834705-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS COMPRISING A CORE AND A RANDOM-COPOLYMER COATING MERCK PATENT GMBH (DE) 2018-12-05 EP disclosed
US-10126625-B2 Particles for electrophoretic displays comprising a core and a random-copolymer coating MERCK PATENT GMBH (DE) 2018-11-13 US disclosed
EP-2850116-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-04-18 EP disclosed
EP-2785797-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-20110310462-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-22 US disclosed
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-15 US disclosed
EP-2393850-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
EP-2393851-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
EP-2393848-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
US-20110297888-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-08 US disclosed
WO-2010089057-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089060-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089059-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089058-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH, (DE) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE EPHX2 431/4885MAPT 3084/4885RAB9A 1993/4885
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, IK, SELP EPHX2 385/4885MAPT 2386/4885RAB9A 1471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.