Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9357384 | 0.77 | DUT (0.56) | ALDH1A1KMT2AMEN1LMNACYP2C19 | |
| SCHEMBL8531246 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL15512301 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL3870579 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1555414 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15512375 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15512201 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL205788 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15512282 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL15512622 | 0.68 | TDP1 (0.73) | ALDH1A1TDP1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371139-B1 | 6-SUBSTITUTED ACYCLICPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENTS | MITSUBISHI CHEM IND (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5112835-A | 6-SUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING THE SAME AS ACTIVE INGREDIENT THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0371139-A1 | 6-SUBSTITUTED ACYCLICPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENTS | Mitsubishi Chemical Corporation (JP) | 1990-06-06 | — | — | EP | disclosed |