Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199461 | 0.82 | SLC1A2 (0.47) | MEN1KMT2A | |
| SCHEMBL199462 | 0.82 | SLC1A2 (0.47) | MEN1KMT2A | |
| SCHEMBL350996 | 0.82 | SLC1A2 (0.47) | MEN1KMT2A | |
| SCHEMBL5203561 | 0.82 | SLC1A2 (0.47) | MEN1KMT2A | |
| SCHEMBL199463 | 0.82 | SLC1A2 (0.47) | MEN1KMT2A | |
| SCHEMBL4780406 | 0.82 | SLC1A2 (0.47) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2297672 | 0.81 | SLC1A2 (0.46) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2297675 | 0.81 | SLC1A2 (0.46) | MEN1KMT2A | |
| SCHEMBL15964095 | 0.79 | KMO (0.49) | CHRNB2CHRNA4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL15956096 | 0.78 | KMO (0.48) | CHRNB2CHRNA4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619807-A1 | NEW BHT ETHER COMPOUNDS AND THEIR USE AS HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC DRUGS | MERTZ + CO., GMBH & CO (DE) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993012089-A1 | NEW BHT ETHER COMPOUNDS AND THEIR USE AS HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC DRUGS | MERZ + CO., GMBH & CO. (DE) | 1993-06-24 | — | — | WO | disclosed |