SCHEMBL350996

SCHEMBL350996

O=C(O)[C@H]1NCC[C@@H]1c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.47
AKR1C3 P42330 1/20 0.41
AKR1C1 Q04828 1/20 0.41
MEN1 O00255 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC4 P56524 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4780406 1.00 SLC1A2 (0.47) SLC1A2AKR1C3AKR1C1MEN1BLM
SCHEMBL5203561 1.00 SLC1A2 (0.47) SLC1A2AKR1C3AKR1C1MEN1BLM
SCHEMBL199463 1.00 SLC1A2 (0.47) SLC1A2AKR1C3AKR1C1MEN1BLM
SCHEMBL199462 1.00 SLC1A2 (0.47) SLC1A2AKR1C3AKR1C1MEN1BLM
SCHEMBL199461 1.00 SLC1A2 (0.47) SLC1A2AKR1C3AKR1C1MEN1BLM
Hydrochloric Acid SCHEMBL2297672 0.98 SLC1A2 (0.46) SLC1A2AKR1C3AKR1C1MEN1BLM
Hydrochloric Acid SCHEMBL2297675 0.98 SLC1A2 (0.46) SLC1A2AKR1C3AKR1C1MEN1BLM
SCHEMBL851578 0.89 MEN1 (0.50) SLC1A2MEN1BLMKMT2A
SCHEMBL16056887 0.89 MEN1 (0.50) SLC1A2MEN1BLMKMT2A
SCHEMBL4074609 0.89 MEN1 (0.50) SLC1A2MEN1BLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
EP-1214345-B1 AGENTS FOR TREATING HUMAN DISEASES, ESPECIALLY FOR TREATING TUMORS SUCH AS COLONIC CANCERS AND MELANOMAS OR FOR REGENERATING TISSUE AND PROMOTING HAIR GROWTH MAX DELBRUECK CENTRUM (DE) 2004-12-29 EP claimed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 US disclosed
US-20250388601-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2025-12-25 US disclosed
US-12358928-B2 Compounds, compositions and methods DENALI THERAPEUTICS INC. (US) 2025-07-15 US disclosed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US disclosed
US-5883077-A PEPTIDES ALDEHYDE ANALOGUES CORVAS INTERNATIONAL, INC. (US) 1999-03-16 US disclosed
WO-1999006434-A1 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS INC. (US) 1999-02-11 WO disclosed
US-5739112-A ANTICOAGULANTS CORVAS INTERNATIONAL, INC. (US) 1998-04-14 US disclosed
WO-1998008815-A1 SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1998-03-05 WO disclosed
WO-1996013266-A1 BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES PROSCRIPT, INC. (US) 1996-05-09 WO disclosed
EP-0675899-A4 NOVEL INHIBITORS OF FACTOR Xa. CORVAS INT INC (US) 1996-01-24 EP disclosed
EP-0675899-A1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1995-10-11 EP disclosed
WO-1994013693-A1 NOVEL INHIBITORS OF FACTOR Xa CORVAS INTERNATIONAL, INC. (US) 1994-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM SLC1A2 2114/4885AKR1C3 4666/4885AKR1C1 4467/4885
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS SLC1A2 78/4885AKR1C3 4010/4885AKR1C1 4270/4885
US-20250388601-A1 Compounds, Compositions and Methods AURKC, WEE2, ERBB2 SLC1A2 3321/4885AKR1C3 703/4885AKR1C1 843/4885
US-12358928-B2 Compounds, compositions and methods PIK3CA, PLK1, PIK3CB SLC1A2 4794/4885AKR1C3 3369/4885AKR1C1 3871/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 SLC1A2 2316/4885AKR1C3 2672/4885AKR1C1 3127/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 SLC1A2 1617/4885AKR1C3 2443/4885AKR1C1 2370/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC SLC1A2 1423/4885AKR1C3 2947/4885AKR1C1 2811/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM SLC1A2 2114/4885AKR1C3 4666/4885AKR1C1 4467/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT SLC1A2 271/4885AKR1C3 2222/4885AKR1C1 2485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.