Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766265 | 0.85 | MAPK1 (0.59) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL27010647 | 0.81 | ALDH1A1 (0.50) | MAPK1ALDH1A1ALOX15GPR174CYP2C19 | |
| SCHEMBL9244855 | 0.78 | MAPK1 (0.59) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL31065567 | 0.77 | MAPK1 (0.59) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL8766309 | 0.77 | MAPK1 (0.64) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL28103978 | 0.76 | MAPK1 (0.85) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| Hydrogen Peroxide SCHEMBL22163808 | 0.76 | MAPK1 (0.94) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL30174380 | 0.76 | MAPK1 (0.61) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL28682767 | 0.75 | MAPK1 (0.67) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A | |
| SCHEMBL28970881 | 0.74 | MAPK1 (0.65) | MAPK1ALDH1A1ALOX15CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322945-B1 | Modification of (co)polymers employing organic peroxides | AKZO NOBEL NV (NL) | 1994-11-02 | — | — | EP | claimed |
| US-5037892-A | Epoxidation Of Olefin Polymers | AKZO N.V. (NL) | 1991-08-06 | — | — | US | claimed |
| EP-0322945-B1 | Modification of (co)polymers employing organic peroxides | AKZO NOBEL NV (NL) | 1994-11-02 | — | — | EP | disclosed |
| US-5202386-A | Adhesion to polar material | AKZO NV (NL) | 1993-04-13 | — | — | US | disclosed |
| US-5037892-A | Epoxidation Of Olefin Polymers | AKZO N.V. (NL) | 1991-08-06 | — | — | US | disclosed |
| EP-0322945-A1 | Modification of (co)polymers employing organic peroxides | Akzo Nobel N.V. (NL) | 1989-07-05 | — | — | EP | disclosed |