Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799573 | 0.96 | TP53 (0.46) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9350861 | 0.89 | MEN1 (0.46) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9727670 | 0.88 | TP53 (0.41) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9658919 | 0.85 | GAA (0.44) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9350725 | 0.82 | GAA (0.43) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9727635 | 0.78 | GAA (0.46) | TP53GAAMEN1KMT2AAKR1C3 | |
| SCHEMBL9727624 | 0.77 | GAA (0.48) | TP53GAAMEN1KMT2AAKR1C3 | |
| SCHEMBL25348950 | 0.77 | MMP2 (0.62) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL7094393 | 0.76 | MMP2 (0.60) | TP53L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9797197 | 0.76 | MEN1 (0.46) | TP53L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384843-B1 | 1-Arylsulfonyl-2-piperidinone derivatives, process and intermediates for their preparation, their pharmaceutical use and compositions containing them | ROUSSEL UCLAF (FR) | 1994-08-31 | — | — | EP | disclosed |
| US-5041436-A | 1-arylsulphonyl-2-piperidinone derivatives, process and intermediates for the preparation thereof, their application as antispasmodics and compositions containing them | ROUSSEL UCLAF (FR) | 1991-08-20 | — | — | US | disclosed |