Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 9/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.34 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL936006 | 0.90 | PIK3CD (0.39) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL935114 | 0.90 | PIK3CD (0.39) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL935884 | 0.89 | PIK3R1 (0.44) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL5607167 | 0.84 | PIK3CD (0.45) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL4414318 | 0.80 | PIK3R1 (0.58) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL4414315 | 0.80 | PIK3R1 (0.58) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31594500 | 0.80 | PIK3R1 (0.58) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31594575 | 0.80 | PIK3R1 (0.58) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL935803 | 0.80 | PIK3R1 (0.46) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL9924638 | 0.79 | PIK3R1 (0.45) | PIK3R1PIK3CAPIK3CDPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456444-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | Intellikine, Inc. (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011008302-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. (US) | 2011-01-20 | — | — | WO | disclosed |