Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298717 | 0.88 | ALDH1A1 (0.34) | TSHRRECQLALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6799570 | 0.69 | SMN1; SMN2 (0.35) | TSHRALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6799568 | 0.69 | SMN1; SMN2 (0.38) | TSHRALDH1A1SMN1; SMN2LMNAAKR1C3 | |
| SCHEMBL23716956 | 0.64 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8779695 | 0.64 | ALDH1A1 (0.50) | TSHRALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL19207389 | 0.62 | ALDH1A1 (0.44) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL27573843 | 0.61 | KDM4E (0.43) | TSHRSMN1; SMN2LMNAKDM4EHSD17B10 | |
| SCHEMBL11742751 | 0.60 | KDM4E (0.42) | TSHRSMN1; SMN2LMNAKDM4EHSD17B10 | |
| Oxirane SCHEMBL4954839 | 0.60 | ALOX15 (0.50) | TSHRALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10917858 | 0.59 | GAA (0.44) | RECQLALDH1A1SMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502820-B1 | New semicarbazides and their use for the stabilization of polyamide fibres and their colours | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| EP-0502820-A1 | New semicarbazides and their use for the stabilization of polyamide fibres and their colours | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | disclosed |