Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359455 | 1.00 | CES1 (0.44) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL9709396 | 0.82 | CES1 (0.47) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL9860999 | 0.82 | CES1 (0.47) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL9709391 | 0.82 | CES1 (0.47) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL3881031 | 0.81 | CES1 (0.64) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL384894 | 0.81 | CES1 (0.64) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL384895 | 0.81 | CES1 (0.64) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL304071 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL304073 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1CYP3A4CYP2C9 | |
| SCHEMBL10193598 | 0.78 | KEAP1 (0.57) | CES1CES2AKR1B1CTBP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242618-B1 | Transparent optical article and process for preparing same | NIPPON OILS & FATS CO LTD (JP) | 1994-11-02 | — | — | EP | claimed |