Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9355594 | 1.00 | NPC1 (0.55) | NPC1RAB9AEPHX2ALDH1A1KDM4E | |
| SCHEMBL2439007 | 0.81 | NPC1 (0.59) | NPC1RAB9AEPHX2ALDH1A1KDM4E | |
| SCHEMBL11880408 | 0.80 | NPC1 (0.57) | NPC1RAB9AEPHX2ALDH1A1KDM4E | |
| SCHEMBL384895 | 0.78 | CES1 (0.64) | EPHX2ALDH1A1HPGDCES2CES1 | |
| SCHEMBL3881031 | 0.78 | CES1 (0.64) | EPHX2ALDH1A1HPGDCES2CES1 | |
| SCHEMBL384894 | 0.78 | CES1 (0.64) | EPHX2ALDH1A1HPGDCES2CES1 | |
| SCHEMBL8059347 | 0.78 | NPC1 (0.54) | NPC1RAB9AEPHX2ALDH1A1KDM4E | |
| SCHEMBL9709177 | 0.77 | EPHX2 (0.51) | EPHX2ALDH1A1KDM4ETAAR1HPGD | |
| SCHEMBL9709173 | 0.77 | EPHX2 (0.51) | EPHX2ALDH1A1KDM4ETAAR1HPGD | |
| SCHEMBL16550684 | 0.77 | MGLL (0.50) | EPHX2HPGDCES2CES1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242618-B1 | Transparent optical article and process for preparing same | NIPPON OILS & FATS CO LTD (JP) | 1994-11-02 | — | — | EP | claimed |