Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521011 | 0.87 | AKR1B1 (0.47) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL9354985 | 0.85 | AKR1B1 (0.56) | AKR1B1CES2CES1MEN1KMT2A | |
| SCHEMBL9355509 | 0.82 | AKR1B1 (0.48) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL6518738 | 0.81 | AKR1B1 (0.44) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL6519461 | 0.81 | ALDH1A1 (0.48) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL6518197 | 0.79 | MEN1 (0.50) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL9355260 | 0.78 | AKR1B1 (0.44) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL6519699 | 0.77 | NPC1 (0.55) | MEN1KMT2AHDAC8HDAC6ALDH1A1 | |
| SCHEMBL7110149 | 0.76 | CES2 (0.41) | AKR1B1KDM4ECES2CES1MEN1 | |
| SCHEMBL6520613 | 0.76 | CYP19A1 (0.48) | AKR1B1CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242618-B1 | Transparent optical article and process for preparing same | NIPPON OILS & FATS CO LTD (JP) | 1994-11-02 | — | — | EP | claimed |