SCHEMBL9355280

SCHEMBL9355280

CC=CC[SiH](c1ccccc1)c1ccccc1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9354491 0.90 POLB (0.30)
SCHEMBL9305085 0.85 MAOB (0.32)
SCHEMBL9306782 0.85 MAOB (0.32)
SCHEMBL10318519 0.76 TSHR (0.35) TSHRACHE
SCHEMBL9637491 0.71 MAOB (0.31)
SCHEMBL18123237 0.68 TSHR (0.43) TSHRACHE
SCHEMBL19335701 0.68 TSHR (0.43) TSHRACHE
SCHEMBL9637408 0.67
SCHEMBL10320358 0.64 TRPA1 (0.32) TSHRACHE
SCHEMBL3297946 0.63 ACHE (0.38) TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460240-B1 CATALYST FOR HYDROGENATION, DEHYDROSILYLATION OR HYDROSILYLATION, AND ITS USE SAGAMI CHEM RES (JP) 1994-11-09 EP disclosed
US-5182246-A Complex metal carbonyl SAGAMI CHEMICAL RESEARCH CENTER (JP) 1993-01-26 US disclosed
EP-0460240-A1 CATALYST FOR HYDROGENATION, DEHYDROSILYLATION OR HYDROSILYLATION, AND ITS USE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-12-11 EP disclosed