Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15528272 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL9357312 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL28758091 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL2549735 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL18418892 | 0.74 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL27895476 | 0.73 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL17282999 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL21964568 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL27912670 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 | |
| SCHEMBL971909 | 0.68 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTNOS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618902-A1 | PROCESS FOR PRODUCING 4,5-DIAMINO PYRAZOLE DERIVATIVES, THEIR USE FOR COLOURING HAIR AND NOVEL PYRAZOLE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994008969-A1 | PROCESS FOR PRODUCING 4,5-DIAMINO PYRAZOLE DERIVATIVES, THEIR USE FOR COLOURING HAIR AND NOVEL PYRAZOLE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |