SCHEMBL9355997

SCHEMBL9355997

CC1(C)CC2CCCC(C1)C2=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9355981 0.84 APLNR (0.38) APLNRMAPT
SCHEMBL14787795 0.74 MAOA (0.35)
SCHEMBL544303 0.74 MAOA (0.35)
SCHEMBL19102322 0.73 MAPK1 (0.33)
SCHEMBL1293264 0.72
SCHEMBL13591096 0.69 DAO (0.39)
SCHEMBL21695107 0.69
SCHEMBL13226520 0.65 SMN1; SMN2 (0.31)
SCHEMBL6749028 0.65 MAPK1 (0.38)
SCHEMBL21220415 0.65 MAPK1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310321-B1 Immunomodulatory azaspiranes SMITHKLINE BEECHAM CORP (US) 1994-11-30 EP disclosed
WO-1989002889-A1 IMMUNOMODULATORY AZASPIRANES SMITHKLINE BECKMAN CORPORATION (US) 1989-04-06 WO disclosed
EP-0310321-A2 Immunomodulatory azaspiranes SMITHKLINE BEECHAM CORPORATION (US) 1989-04-05 EP disclosed