Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186487 | 0.83 | ALDH1A1 (0.78) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| Tritiozine SCHEMBL1170764 | 0.81 | MAPT (1.00) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL6456595 | 0.81 | L3MBTL1 (0.73) | ALDH1A1HPGDSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9174229 | 0.77 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL9356116 | 0.76 | MAPT (0.68) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL9356614 | 0.75 | MAPT (0.76) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| Vanitiolide SCHEMBL1643547 | 0.74 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL10780664 | 0.74 | ALDH1A1 (0.60) | MAPTALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL19357090 | 0.72 | L3MBTL1 (0.71) | ALDH1A1SMN1; SMN2KMT2ALMNAATM | |
| SCHEMBL3576242 | 0.72 | L3MBTL1 (0.64) | ALDH1A1HPGDSMN1; SMN2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492484-B1 | Substituted N-[phenyl-(thioxomethyl)]-morpholine derivatives, a process for preparing them as well as compositions containing these compounds and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1994-11-09 | — | — | EP | disclosed |