Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012958 | 0.79 | KMT2A (0.56) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL13981872 | 0.78 | ACHE (0.42) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL9356659 | 0.76 | ALPG (0.70) | ALDH1A1KDM4EGAAMAPTPOLB | |
| SCHEMBL20033130 | 0.74 | PDE4B (0.44) | ALDH1A1KDM4EMAPTCYP2D6CYP1A2 | |
| SCHEMBL26921558 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL11837908 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAMAPTCYP2D6 | |
| SCHEMBL11111092 | 0.73 | TSHR (0.64) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL2616297 | 0.73 | KMT2A (0.76) | ALDH1A1KDM4ETSHRCYP1A2CYP2C19 | |
| SCHEMBL9198139 | 0.73 | ALDH1A1 (0.64) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL9651777 | 0.73 | TSHR (0.64) | ALDH1A1KDM4EGAATSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416410-B1 | Piperaziniocephalosporins | SHIONOGI & CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5143910-A | PIPERAZINIOCEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0416410-A1 | Piperaziniocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-03-13 | — | — | EP | disclosed |