Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356192 | 0.86 | CNR1 (0.53) | P2RX4ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL5560196 | 0.84 | CNR1 (0.50) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL27942329 | 0.81 | P2RX4 (0.56) | P2RX4ALDH1A1KDM4EGABRA5SMN1; SMN2 | |
| SCHEMBL15329829 | 0.79 | P2RX4 (0.53) | P2RX4ALDH1A1KDM4EGABRA5SMN1; SMN2 | |
| SCHEMBL16627676 | 0.78 | P2RX4 (0.52) | P2RX4KDM4EGABRA5SMN1; SMN2GAA | |
| SCHEMBL27806397 | 0.77 | P2RX4 (0.51) | P2RX4GABRA5SMN1; SMN2GAAPOLB | |
| SCHEMBL27204179 | 0.76 | KDM4E (0.58) | P2RX4ALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL2863880 | 0.76 | P2RX4 (0.62) | P2RX4ALDH1A1KDM4EGABRA5SMN1; SMN2 | |
| SCHEMBL27946553 | 0.75 | KMT2A (0.73) | P2RX4ALDH1A1KDM4EGABRA5SMN1; SMN2 | |
| SCHEMBL18257930 | 0.75 | P2RX4 (0.54) | P2RX4ALDH1A1KDM4ESMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625144-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993015056-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |