Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806397 | 0.89 | P2RX4 (0.51) | P2RX4AHRKMT2AMEN1GABRA5 | |
| SCHEMBL16627682 | 0.86 | CNR1 (0.48) | KMT2ACNR1CNR2CCR2FEN1 | |
| SCHEMBL27942329 | 0.81 | P2RX4 (0.56) | P2RX4KMT2AMEN1GABRA5POLB | |
| SCHEMBL16627834 | 0.80 | KMT2A (0.53) | KMT2AMEN1POLBGAASMN1; SMN2 | |
| SCHEMBL16627581 | 0.80 | CNR1 (0.54) | AHRKMT2AMEN1CNR1CNR2 | |
| SCHEMBL15329829 | 0.79 | P2RX4 (0.53) | P2RX4KMT2AMEN1GABRA5POLB | |
| SCHEMBL3964251 | 0.79 | CCR2 (0.74) | P2RX4KMT2APOLBCCR2 | |
| SCHEMBL29433700 | 0.79 | CCR2 (0.74) | P2RX4KMT2APOLBCCR2 | |
| SCHEMBL9356151 | 0.78 | P2RX4 (0.52) | P2RX4KMT2AMEN1GABRA5POLB | |
| SCHEMBL16627579 | 0.78 | CCR2 (0.51) | GAASMN1; SMN2CNR1CNR2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |